HP MODEL — PROTEIN FOLDING

2D Lattice · Monte Carlo Energy Minimization · Hydrophobic Core
Energy: 0 | H-H contacts: 0
H (hydrophobic) residues gain −1 energy per non-bonded H-H contact. P (polar) residues are neutral. Monte Carlo explores conformations at temperature kT. Low temperature drives collapse into compact hydrophobic core — the folding funnel.