Hodgkin-Huxley Action Potential

Voltage-gated ion channels · Na⁺ and K⁺ conductance dynamics

STIMULUS

PARAMETERS

LEGEND

Voltage V (mV)
m: Na⁺ activation
h: Na⁺ inactivation
n: K⁺ activation
I_Na current
I_K current
HH Model (1952):
C_m dV/dt = I_ext − g_Na·m³h(V−E_Na) − g_K·n⁴(V−E_K) − g_L(V−E_L)

Na⁺ channels activate fast (m) and inactivate slower (h). K⁺ channels activate with delay (n). The interplay generates the action potential spike.