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Genetic Drift
Population N
200
Initial freq p₀
0.50
Selection s
0.00
Mutation μ
0.001
Bottleneck gen
off
Trajectories
10
Theory
Fix. prob P(fix) =
—
E[fix time] =
—
gen
Results
Fixed A₁:
0
Fixed A₂:
0
Segregating:
0
Run
Auto-run
Wright-Fisher model: next gen sampled from binomial(N, p') where
p' = p(1+s)/(1+sp)
+ mutation: p→p(1−μ)+μ(1−p)
Kimura fixation prob:
P(fix) ≈ 2s for new mutation
= 1/(2N) for neutral (s=0)
Expected fixation time:
≈ 4N generations (neutral)