Michaelis-Menten Enzyme Kinetics

V_max, K_m, inhibition modes, Hill cooperativity

V_max100

K_m (mM)5

Hill n1.0

Inhibitor conc.0

Inhibition type

K_i10

v = V_max·[S]ⁿ / (K_mⁿ + [S]ⁿ)

The Michaelis-Menten equation describes enzyme reaction velocity as a function of substrate concentration. K_m is the substrate concentration at half-maximal velocity. Hill coefficient n>1 indicates positive cooperativity. Competitive inhibition raises apparent K_m; noncompetitive inhibition lowers V_max.