Layer Functions
I — Molecular: distal dendrites, horizontal connections
II/III — Superficial: cortico-cortical output, callosal
IV — Granular: thalamic input, spiny stellate cells
V — Infragranular: corticospinal, Betz cells, basal ganglia
VI — Deep: corticothalamic feedback, claustrum
Thalamus → Layer IV
Primary sensory input arrives here first.
Minicolumn
~80–100 neurons sharing similar receptive fields, stacked radially.
I — Molecular: distal dendrites, horizontal connections
II/III — Superficial: cortico-cortical output, callosal
IV — Granular: thalamic input, spiny stellate cells
V — Infragranular: corticospinal, Betz cells, basal ganglia
VI — Deep: corticothalamic feedback, claustrum
Thalamus → Layer IV
Primary sensory input arrives here first.
Minicolumn
~80–100 neurons sharing similar receptive fields, stacked radially.