Cell Polarity via Turing Mechanism

An activator-inhibitor reaction-diffusion system on a 1D cell membrane spontaneously breaks symmetry, establishing a polarized state. The activator (A) self-amplifies locally while the inhibitor (H) diffuses faster, creating a single concentration peak — the cell's "front".

Activator (A) — blue  |  Inhibitor (H) — orange
Space-time plot (activator)
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0.150
0.080
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Gierer-Meinhardt model (1D):
∂A/∂t = D_A ∂²A/∂x² + a·A²/H − b·A + noise
∂H/∂t = D_H ∂²H/∂x² + a·A² − b·H

Turing instability requires D_H ≫ D_A. The homogeneous steady state (A₀, H₀) becomes unstable to spatially heterogeneous perturbations when the inhibitor diffuses fast enough to suppress activator globally while the activator amplifies locally. For a cell, this spontaneously selects one end as the "front".