CATALYTIC CYCLE

Turnover mechanism · energy landscape · TON/TOF · Sabatier volcano plot
Sabatier Principle
Optimal binding: not too strong
(poison the surface) nor too weak
(no adsorption).

TOF = turnovers per second
TON = total turnovers before death

Rate ≈ A·e^(−Ea/kT)
Ea = activation energy

BEP relation: Ea ∝ ΔH_rxn
(Brønsted-Evans-Polanyi)